Excipient for ODTs
PHARMACEUTICAL EXCIPIENT FOR RAPID ORAL DESINTEGRATION TABLETS (ODT)
DESCRIPTION
This technology describes the use of an excipient, consisting of a polyalcohol and a water soluble polymer, which favors disintegration/dissolution of oral tablets in the oral cavity in just a few seconds, with no need to ingest water.
APPLICATIONS
Excipient for of oral tablets of fast disintegration and/or dissolution | Suitable to formulate tables with active ingredients, flavorings and colorants
ADVANTAGES
• Fast disintegration and dissolution, maintaining the hardness of the tablet
• Pleasant taste
• Easy compacting and uniform size
• Simple to obtain, avoiding the use of organic solvents
• Easy to scale up
• Water-soluble
• Low cost and easy accessibility
DEVELOPMENT STATUS
Proof of concept has been accomplished and the product is ready for scale-up.
INTELLECTUAL PROPERTY STATUS
Application number: AR2012P101793/2012 & PCT/IB2013/054188
RESEARCHERS
M. Verónica Ramirez Rigo, Juliana Piña, Verónica Bucalá et al.